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Crystallization of Pharmaceutical Crystals

Abstract : The aim of this chapter is to provide students as well as industrial and academic research scientists who intend to tackle crystallization of pharmaceutical crystals with theory and practical examples. Crystallization involves two separate processes, nucleation and growth, which are rarely completely unconnected. Here, we give theoretical background and concrete examples illustrating the crystallization of active pharmaceutical ingredients and intermediates, and make recommendations for the development of a crystallization process at laboratory scale.
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Submitted on : Friday, February 12, 2016 - 10:52:24 AM
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S. Veesler, François Puel. Crystallization of Pharmaceutical Crystals. Tatau Nishinaga. Handbook of Crystal Growth, 1-A (Chapitre 21), Elsevier, pp.915-949, 2014, Fundamentals : Thermodynamics and Kinetics, 9780444563699. ⟨10.1016/B978-0-444-56369-9.00021-6⟩. ⟨hal-01273239⟩



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