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Towards a realistic and integrated strain design in batch bioreactor

Abstract : Recent advances in modeling bacterial cell functioning have deeply renewed questions about bioprocess design and opens the way towards the development of computer aided design (CAD) for strains. This article aims at explaining and exploring the consequences opened by the new cell models, investigating the questions related to the biological implementation of optimal strategies and in conclusion the possible role of the complex regulatory network in the retuning of the strain.
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https://hal-centralesupelec.archives-ouvertes.fr/hal-02111237
Contributor : Didier Dumur <>
Submitted on : Thursday, March 12, 2020 - 11:32:19 AM
Last modification on : Wednesday, September 16, 2020 - 9:00:05 PM
Long-term archiving on: : Saturday, June 13, 2020 - 2:16:30 PM

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Guillaume Jeanne, Anne Goelzer, Sihem Tebbani, Didier Dumur, Vincent Fromion. Towards a realistic and integrated strain design in batch bioreactor. 57th IEEE Conference on Decision and Control (CDC 2018), Dec 2018, Miami, United States. ⟨hal-02111237⟩

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